Acquired Factor X Deficiency Associated with Atypical AL-amyloidosis

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Acquired Factor X Deficiency Associated with Systematized Amyloidosis - A Report

C OAGULATION DEFECTS due to the lack of a single blood clotting factor are almost exclusively congenital and symptoms appear in early life. Acquired defects other than iatrogenic are usually the result of liver dysfunction and in such cases more than one clotting factor is depressed. A case of selective factor X deficiency developing in middle life and associated with extensive amyloidosis has ...

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Splenectomy in an uraemic patient with acquired factor X deficiency due to AL amyloidosis.

The clinical signs of amyloidosis are dependent on the organ systems involved [I]. A common finding is renal involvement which manifests as nephrotic syndrome. Cardiac involvement may result in congestive cardiomyopathy with conduction defects and arrhythm ias. Amyloid deposits especially in the spleen may bind clotting factors , which can lead to coagulation abnormaliti es. Factor X deficiency...

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Spontaneous perinephric hematoma due to acquired factor X deficiency in AL amyloidosis

Spontaneous perinephric hematoma (SPH) is a rare entity whose diagnosis is challenging because of its varied clinical presentation and lack of any specific etiology. We report a 34-year-old African-American male who presented with left flank pain and was found to have a large left perinephric hematoma, in the setting of undiagnosed AL amylodosis. The case illustrates that while a SPH due to the...

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Acquired factor X deficiency associated with systematized amyloidosis--a report of a case.

C OAGULATION DEFECTS due to the lack of a single blood clotting factor are almost exclusively congenital and symptoms appear in early life. Acquired defects other than iatrogenic are usually the result of liver dysfunction and in such cases more than one clotting factor is depressed. A case of selective factor X deficiency developing in middle life and associated with extensive amyloidosis has ...

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Factor X deficiency: An uncommon presentation of AL amyloidosis

Factor X deficiency is the most common coagulation factor deficiency amongst patients with AL amyloidosis. It presumably occurs due to adsorption of factor X to amyloid fibrils. The deficiency of this factor, in conjunction with other hemostatic defects, can cause bleeding complications. A case of acquired factor X deficiency due to AL amyloidosis is reported, where abnormal coagulation paramet...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2014

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.53.2191